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1

Perspectives on the Use of Data Mining in Pharmacovigilance

Dr June Almenoff, Joseph M. Tonning, A. Lawrence Gould, Ana Szarfman, Manfred Hauben, Rita Ouellet-Hellstrom, Robert Ball, Ken Hornbuckle, Louisa Walsh, Chuen Yee, Susan T. Sacks, Nancy Yuen, Vaishali

Journal:

Year:

2005

Language:

english

File:

PDF, 267 KB

english, 2005

2

Evolving Paradigms in Pharmacovigilance

Brewster, Wendy, Gibbs, Trevor, LaCroix, Karol, Murray, Alison, Tydeman, Michael, Almenoff, June

Journal:

Year:

2006

Language:

english

File:

PDF, 85 KB

english, 2006

3

Disproportionality analysis using empirical Bayes data mining: a tool for the evaluation of drug interactions in the post-marketing setting

June S. Almenoff, William DuMouchel, L. Allen Kindman, Xionghu Yang, David Fram

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2003

Language:

english

File:

PDF, 62 KB

english, 2003

4

Letter to the Editor—Re: Almenoff et al., ‘Disproportionality analysis using empirical Bayes data mining: a tool for the evaluation of drug interactions in the post-marketing setting’, (PDS, 2003; 12(6); 517–521)

June S. Almenoff, William DuMouchel, L. Allen Kindman, Xionghu Yang, David Fram

Journal:

Pharmacoepidemiology and Drug Safety

Year:

2004

Language:

english

File:

PDF, 29 KB

english, 2004

5

Ligand-based histochemical localization and capture of cells expressing heat-stable enterotoxin receptors

June S. Almenoff, Sabrina I. Williams, Lawrence A. Scheving, Amrit K. Judd, Gary K. Schoolnik

Journal:

Molecular Microbiology

Year:

1993

Language:

english

File:

PDF, 3.69 MB

english, 1993

6

Biochemical and Immunological Properties of a Membrane-Bound Brain Metalloendopeptidase: Comparison with Thermolysin-Like Kidney Neutral Metalloendopeptidase

June Almenoff, Marian Orlowski

Journal:

Journal of Neurochemistry

Year:

1984

Language:

english

File:

PDF, 818 KB

english, 1984

7

Molecular clinical safety intelligence: a system for bridging clinically focused safety knowledge to early-stage drug discovery – the GSK experience

Dana E. Vanderwall, Nancy Yuen, Mohammad Al-Ansari, James Bailey, David Fram, Darren V.S. Green, Stephen Pickett, Giovanni Vitulli, Juan I. Luengo, June S. Almenoff

Journal:

Drug Discovery Today

Year:

2011

Language:

english

File:

PDF, 976 KB

english, 2011

8

Clinical significance of serum thermolysin-like metalloendopeptidase and its relationship to serum angiotensin converting enzyme in sarcoidosis

June Almenoff, Alvin S. Teirstein

Journal:

The American Journal of Medicine

Year:

1987

Language:

english

File:

PDF, 630 KB

english, 1987

9

High density lipoprotein cholesterol is reduced in patients with sarcoidosis

L.Allen Kindman, Harriet S. Gilbert, June S. Almenoff, Henry Ginsberg, Richard Fagerstrom, Alvin S. Teirstein

Journal:

The American Journal of Medicine

Year:

1989

Language:

english

File:

PDF, 444 KB

english, 1989

10

Inhibitors of an enkephalin degrading membrane-bound metalloendopeptidase: Analgesic properties and effects on striatal enkephalin levels

Leelavati R. Murthy, Stanley D. Glick, June Almenoff, Sherwin Wilk, Marian Orlowski

Journal:

European Journal of Pharmacology

Year:

1984

Language:

english

File:

PDF, 646 KB

english, 1984

11

Association of asthma therapy and churg-strauss syndrome: An analysis of postmarketing surveillance data

William DuMouchel, Eric T. Smith, Richard Beasley, Harold Nelson, Xionghu Yang, David Fram, June S. Almenoff

Journal:

Clinical Therapeutics

Year:

2004

Language:

english

File:

PDF, 1.05 MB

english, 2004

12

Membrane bound pituitary metalloendopeptidase: Apparent identity to enkephalinase

June Almenoff, Sherwin Wilk, Marian Orlowski

Journal:

Biochemical and Biophysical Research Communications

Year:

1981

Language:

english

File:

PDF, 535 KB

english, 1981

13

Analgesic Properties and Effects on Striatal Enkephalin Levels of Inhibitors of Membrane-Bound Metalloendopeptidase

LEELAVATI R. MURTHY, STANLEY D. CLICK, JUNE ALMENOFF, SHERWIN WILK, MARIAN ORLOWSKI

Journal:

Annals of the New York Academy of Sciences

Year:

1984

Language:

english

File:

PDF, 126 KB

english, 1984

14

Thermolysin-like Serum Metalloendopeptidase : A New Marker for Active Sarcoidosis That Complements Serum Angiotensin-converting Enzyme

JUNE ALMENOFF, MARY LOU SKOVRON, ALVIN S. TEIRSTEIN

Journal:

Annals of the New York Academy of Sciences

Year:

1986

Language:

english

File:

PDF, 347 KB

english, 1986

15

Cerebral Sparganosis: Case Report and Review

Mark Holodniy, June Almenoff, Jeffery Loutit and Gary K. Steinberg

Journal:

Reviews of Infectious Diseases

Year:

1991

Language:

english

File:

PDF, 616 KB

english, 1991

16

Comparative Performance of Two Quantitative Safety Signalling Methods

Dr June S. Almenoff, Karol K. LaCroix, Nancy A. Yuen, David Fram…

Journal:

Year:

2006

Language:

english

File:

PDF, 138 KB

english, 2006

17

Innovations for the Future of Pharmacovigilance

Dr June S. Almenoff

Journal:

Year:

2007

Language:

english

File:

PDF, 56 KB

english, 2007

18

Eluxadoline Benefits Patients With Irritable Bowel Syndrome With Diarrhea in a Phase 2 Study

Dove, Leonard S., Lembo, Anthony, Randall, Charles W., Fogel, Ronald, Andrae, David, Davenport, J. Michael, Mcintyre, Gail, Almenoff, June S., Covington, Paul S.

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 1.36 MB

english, 2013

19

929d Eluxadoline for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome: Results of 2 Randomized, Double-blind, Placebo-Controlled Phase 3 Clinical Trials of Efficacy and Safety

Lembo, Anthony, Dove, Scott, Andrae, David, Davenport, J. Michael, McIntyre, Gail, Almenoff, June, Covington, Paul S.

Journal:

Gastroenterology

Year:

2014

Language:

english

File:

PDF, 50 KB

english, 2014

20

Molecular Cloning and Characterization of SCaMPER, a Sphingolipid Ca2+Release-Mediating Protein from Endoplasmic Reticulum

Cungui Mao, Stella H. Kim, June S. Almenoff, X. L. Rudner, Denise M. Kearney and L. Allen Kindman

Journal:

Proceedings of the National Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 825 KB

english, 1996

21

Membrane-bound kidney neutral metalloendopeptidase: interaction with synthetic substrates, natural peptides, and inhibitors

Almenoff, June, Orlowski, Marian

Journal:

Year:

1983

Language:

english

File:

PDF, 2.08 MB

english, 1983

22

Biogenesis, Cellular Localization, and Functional Activation of the Heat-Stable Enterotoxin Receptor (Guanylyl Cyclase C) †

Rudner, Xiaowen L., Nicchitta, Christopher, Almenoff, June S.

Journal:

Year:

1996

Language:

english

File:

PDF, 332 KB

english, 1996

23

[ACM Press the ninth ACM SIGKDD international conference - Washington, D.C. (2003.08.24-2003.08.27)] Proceedings of the ninth ACM SIGKDD international conference on Knowledge discovery and data mining - KDD '03 - Empirical Bayesian data mining for discovering patterns in post-marketing drug safety

Fram, David M., Almenoff, June S., DuMouchel, William

Year:

2003

Language:

english

File:

PDF, 450 KB

english, 2003

24

Regulation of Cell Signaling by the Cytoplasmic Domains of the Heat-Stable Enterotoxin Receptor: Identification of Autoinhibitory and Activating Motifs

Xiaowen L. Rudner, Kathryn K. Mandal, Fred J. De Sauvage, L. Allen Kindman and June S. Almenoff

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.10 MB

english, 1995

25

Clinical Safety of RHB-105: A Novel Rifabutin Based Triple Therapy for the Treatment of Helicobacter pylori Infection

Kalfus, Ira N., Bullock, Jeff, Almenoff, June, Anderson, Patricia, Graham, David Y.

Journal:

American Journal of Gastroenterology

Year:

2019

File:

PDF, 165 KB

2019

26

S1342âEfficacy of H. pylori Eradication by Low-Dose Rifabutin Triple Therapy (RHB-105) Is Unaffected by BMI: Post-hoc Analysis From Two Phase 3 Trials

Sheldon, Kely L., Moss, Steven, Al Samman, Mohd Amer, Offman, Elliot, Panas, Raymond M., Almenoff, June

Journal:

American Journal of Gastroenterology

Year:

2020

File:

PDF, 270 KB

2020